NorthWest Biotherapeutics Inc (NWBO)

[RRP60]

Gary, briefly touching your last paragraph, in real world, bones are frequently involved  in breast cancers as metastatic disease. When they respond to treatments, the body will try to regenerate bone minerals there to remodel those lesions. This bony remodeling will be seen as persistant bone lesions in imaging studies.  Many a times these lesions will stay back inspite of improvement in the soft tissue lesions and improvement in tumor markers. When we subject these patients to hybrid imaging , these turn out to be inactive lesions with healing blastic component in these bone lesions. Nothing need to be done. Well once we get approval for dcvax l and D along with activated dcells and checkpoint inhibitor combinations, so much can be done in terms of off label use at every hospital level for the smoldering disease or recurrence. We have already come a long way in tackling breast cancer , this is what i saw over the years. Its still a dreadful condition. But with the available treatment options and newer imaging techniques, patients are getting so much of hope. Once we get our treatments to the market, many of these patients will out live these cancers. Iam more than positive about this.