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Re: eagle8 post# 806323

Friday, 01/02/2026 11:50:06 AM

Friday, January 02, 2026 11:50:06 AM

Post# of 819726

Clinical development requires the opposite. It requires freedom to adjust protocols mid-trial, to respond to immune phenotyping, to test combinations, and to refine dosing and sequencing without triggering regulatory resets. It also benefits from a fundamentally different cost structure. The Pittsburgh Innovation Core operates under a capital-light model: academic grant support tied to Dr. Kalinski’s NIH-funded programs, institutional cost-sharing through UPMC, and clinical-trial and compassionate-use manufacturing that does not require commercial-scale staffing or release overhead.



Makes perfect sense!!
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