NorthWest Biotherapeutics Inc (NWBO)

[CherryTree1]

Very informative ASM. It was well worth listening to Linda.
Here is a very very quick summary for anyone who missed it.
Linda gave a very good appreciation for the huge complexity, huge time expenditures and huge cost associated with every part of what they are doing (e.g. MRHA, Direct transition and ready to go (but spending money on manufacturing expansion vs Direct phase-2 first), Reading B-suites for commercialization, Getting C-suites up and running for future manufacturing simplification and capacity improvements including a simplified C-suite,
Clarified that they are focused on getting through MRHA for approval as their primary most important goal and then other focus areas will spring from MRHA approval.
Clarified that if and when approved they will use B-suites systems to manufacture DCVAX-L
From readying many of the posts on the board it is clear that many do not appreciate the huge expenses the must incur (e.g. $12 million on consultant for MRHA, $100 million on patents, $1 million for each piece of C-suite equipment with lead time well over a year, just to name a few).
They also run into issue like the first 2 engineers re-engineered Flaskworks systems making it 2 feet longer without being asked to do that which resulted in it no long fit the foot print so they had to bring in 2 new engineer to do the work instead.
Advent is wholly owned by NWBO clarification.
Additional 900 million shares are for flexibility not to just issue willy-nilly in short order. Focus will be non-delutive,
Expanding compassionate use including using DCVAX for other non-GBM cancers. They will be staring combo trials including Ovarian Cancer trial. There may be a new regional partnership in near future (not yet firm).
They also have a boat load of consultants that have been working with then for years that will join the management team immediately if and when they get approval.