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Re: ATLnsider post# 802623

Friday, 12/12/2025 2:32:40 PM

Friday, December 12, 2025 2:32:40 PM

Post# of 817838
ATL, absolutely! It appears that a facility in Pittsburgh won the contract for NWBO business, based on the fact that NWBO is now looking to hire two more experts in cell technology: a senior scientist and a technician. As you said, for the last few quarters NWBO's SEC filings have kept us informed about their search for a facility to continue work and clinical trials on the cell therapy they purchased from Roswell and the University of Pittsburgh. In fact it makes lots of sense that they would go with a facility in Pittsburgh where this new technology originated. A few quarters ago management told us they had hired the person to run this facility. I would not be surprised if it's someone who worked on the development of the Pittsburgh DCs. (Dr. K?? I can't remember the spelling of his name.)
BioForce makes the most sense to me based on quick reads and their affiliation with University of Pittsburgh. Here's one online description I read about BioForce:

Key Players & Opportunities in Pittsburgh:
University of Pittsburgh (Pitt) & ElevateBio: This major partnership is building the BioForge Biomanufacturing Center, a large facility for cell/gene therapy development and manufacturing, attracting other biotechs and creating a central hub.



This is what ElecateBio says about itself:

We’re building the future of medicine by combining two essential capabilities: gene editing technologies and the expertise to manufacture complex therapies at scale. Through partnerships with biopharma companies, we provide the tools, facilities, and knowledge needed to develop genetic medicines faster and more efficiently, accelerating their delivery to patients worldwide.



Here's another quote from them:

We are more than a traditional CDMO at ElevateBio BaseCamp®. We are a skilled partner offering the expertise, technologies, and state-of-the-art facilities to provide manufacturing solutions for cell and gene therapies, from preclinical through commercial production.



I don't think gene editing fits with DCVax technology, but it appears they have state-of-the-art facilities for large-scale manufacturing.
Also, it appears that BioForce is recruiting companies to set up shop with them, so perhaps NWBO future includes creating its own GMP space there. But that's just me speculating into the future.
This trail of posts include a URL that lists over 40 cell and gene therapy companies, so please look through them to see if any of these companies could have synergy with DCVax. Maybe one of them would look like a more likely site for NWBO to put down roots in the US.

Also remember, NWBO is talking about continuing clinical trials and research on DCVax-Direct and the in-licensed technology for Roswell and U. of Pitt at this US site. I have suggested here that this clinical work gives us a foothold toward eventual commercialization but, again, that's just me thinking into the future.


This is the most recent November 2025 10K:

Manufacturing in the US for In-licensed Technologies. Based upon further assessments of the two candidate GMP manufacturing locations in the US which the Company had previously narrowed down to as finalists, the Company finalized its selection and undertook contract negotiations to secure the selected location and to allocate operational responsibilities. The Company continued the hiring process for personnel with the special types of expertise and prior experience needed for the initial core operating team for this location.

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