Thursday, November 13, 2025 7:40:36 PM
Tomorrow should be an interesting day, though I'm not expecting anything in particular here. As most I believe know my other major biotech investment is AVXL which has been down substantially as we approach tomorrow. Why? Because tomorrow the European advisory committee will make a recommendation to the regulators to either approve, or not. It's fairly certain the regulators will go along with whatever the committee recommends in roughly 30 to 60 days.
It's a question because like our results, their results aren't perfect. I have little doubt that many with Alzheimer's are benefitting from their drug, much the same way many here are benefitting with DCVax-L. No doubt, in both companies there is some doubt, but if there weren't, both companies would be trading dramatically higher than they are now, and the potential to go dramatically higher on approval wouldn't be nearly as great as approval would be built into their price.
It's unfortunate, but new groundbreaking technology almost always involves taking risk while tweaking an existing product for slight improvement is nearly a sure thing for approval, though it doesn't greatly move the stock price. it keeps the customers coming. It certainly has greater risk to invest in newer dynamic technology, in IMGN it took nearly 4 decades, but it does pay off and I believe that both these companies have the same sort of potential, but I didn't invest in them decades ago when they were totally in their infancy. I'll know tomorrow if AVXL could gain approval shortly, and I really don't think it will be that much longer before we know about NWBO.
Gary
It's a question because like our results, their results aren't perfect. I have little doubt that many with Alzheimer's are benefitting from their drug, much the same way many here are benefitting with DCVax-L. No doubt, in both companies there is some doubt, but if there weren't, both companies would be trading dramatically higher than they are now, and the potential to go dramatically higher on approval wouldn't be nearly as great as approval would be built into their price.
It's unfortunate, but new groundbreaking technology almost always involves taking risk while tweaking an existing product for slight improvement is nearly a sure thing for approval, though it doesn't greatly move the stock price. it keeps the customers coming. It certainly has greater risk to invest in newer dynamic technology, in IMGN it took nearly 4 decades, but it does pay off and I believe that both these companies have the same sort of potential, but I didn't invest in them decades ago when they were totally in their infancy. I'll know tomorrow if AVXL could gain approval shortly, and I really don't think it will be that much longer before we know about NWBO.
Gary
Bullish
Recent NWBO News
- Northwest Biotherapeutics Appoints Dr. Annalisa Jenkins As Strategic Adviser To Advance Dendritic Cell Cancer Vaccine Platform • PR Newswire (US) • 04/30/2026 04:38:00 PM
- Northwest Biotherapeutics Appoints Dr. Annalisa Jenkins As Strategic Adviser To Advance Dendritic Cell Cancer Vaccine Platform • PR Newswire (US) • 04/30/2026 04:30:00 PM
- Northwest Biotherapeutics Announces Establishment Of the Company's Own Dedicated Leukapheresis Clinic • PR Newswire (US) • 04/21/2026 01:30:00 PM
- Northwest Biotherapeutics Announces Establishment Of the Company's Own Dedicated Leukapheresis Clinic • PR Newswire (US) • 04/21/2026 01:30:00 PM
- Form EFFECT - Notice of Effectiveness • Edgar (US Regulatory) • 04/21/2026 04:15:08 AM
- Form POS AM - Post-Effective amendments for registration statement • Edgar (US Regulatory) • 04/16/2026 09:25:30 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 04/07/2026 04:30:50 PM
- Form NT 10-K - Notification of inability to timely file Form 10-K 405, 10-K, 10-KSB 405, 10-KSB, 10-KT, or 10-KT405 • Edgar (US Regulatory) • 03/31/2026 09:04:37 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 01/15/2026 10:06:20 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 01/02/2026 10:14:59 PM
- Form DEF 14A - Other definitive proxy statements • Edgar (US Regulatory) • 11/28/2025 09:43:27 PM
- Form 424B5 - Prospectus [Rule 424(b)(5)] • Edgar (US Regulatory) • 11/25/2025 10:23:07 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 11/20/2025 09:26:03 PM
- Form PRE 14A - Other preliminary proxy statements • Edgar (US Regulatory) • 11/19/2025 09:15:48 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 11/14/2025 09:44:21 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/31/2025 04:29:10 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/30/2025 08:40:05 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/24/2025 04:28:38 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/14/2025 06:22:26 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 08/14/2025 09:00:38 PM
- Form 424B5 - Prospectus [Rule 424(b)(5)] • Edgar (US Regulatory) • 07/01/2025 09:04:38 PM
