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Re: Doc328 post# 507533

Thursday, 11/13/2025 1:23:06 PM

Thursday, November 13, 2025 1:23:06 PM

Post# of 517548
point taken - about 75%?

AVXL submitted information that IMO mitigates potential bias: MRI, biomarkers, and OLE data that is independent of dropout rates. imaging and biomarker data and OLE data. All of this information independenly confirms efficacy. Risk/benefit analysis doesn't seem that tough direct CHMP to make the right decision for patients, Doc. Perfection can't be the enemy of the good here. We're talking about people's lives!
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