| Followers | 8 |
| Posts | 3250 |
| Boards Moderated | 0 |
| Alias Born | 04/21/2025 |
Saturday, November 08, 2025 7:01:32 AM
Why is that interesting? DCVax L was developed by UCLA via Liau and Prins ... NWBO licenses it from them.
DCVax L is the ONLY product that NWBO licenses from UCLA.
"DCVax (specifically DCVax-L) and ATL-DC are both autologous tumor lysate-pulsed dendritic cell (DC) vaccines targeting glioblastoma (GBM), but they are distinct products developed and manufactured by separate entities, with no direct equivalence or shared production for their respective trials.Key Differences:Developer and Ownership:DCVax-L is the proprietary product of Northwest Biotherapeutics (NWBO), a Maryland-based biotech company. It's their lead candidate in a Phase 3 trial (NCT00045968) for newly diagnosed and recurrent GBM, involving over 300 patients across multiple sites.
ATL-DC is an investigational vaccine developed by researchers at UCLA (primarily through the lab of Dr. Robert Prins and collaborators like Dr. Linda Liau), under UCLA's Specialized Programs of Research Excellence (SPORE) in brain cancer. It's used in smaller Phase 1 trials, such as one combining it with pembrolizumab (Keytruda) for recurrent, surgically accessible GBM (NCT04201873)."
DCVax L is the ONLY product that NWBO licenses from UCLA.
"DCVax (specifically DCVax-L) and ATL-DC are both autologous tumor lysate-pulsed dendritic cell (DC) vaccines targeting glioblastoma (GBM), but they are distinct products developed and manufactured by separate entities, with no direct equivalence or shared production for their respective trials.Key Differences:Developer and Ownership:DCVax-L is the proprietary product of Northwest Biotherapeutics (NWBO), a Maryland-based biotech company. It's their lead candidate in a Phase 3 trial (NCT00045968) for newly diagnosed and recurrent GBM, involving over 300 patients across multiple sites.
ATL-DC is an investigational vaccine developed by researchers at UCLA (primarily through the lab of Dr. Robert Prins and collaborators like Dr. Linda Liau), under UCLA's Specialized Programs of Research Excellence (SPORE) in brain cancer. It's used in smaller Phase 1 trials, such as one combining it with pembrolizumab (Keytruda) for recurrent, surgically accessible GBM (NCT04201873)."
Recent NWBO News
- Northwest Biotherapeutics Announces Establishment Of the Company's Own Dedicated Leukapheresis Clinic • PR Newswire (US) • 04/21/2026 01:30:00 PM
- Northwest Biotherapeutics Announces Establishment Of the Company's Own Dedicated Leukapheresis Clinic • PR Newswire (US) • 04/21/2026 01:30:00 PM
- Form EFFECT - Notice of Effectiveness • Edgar (US Regulatory) • 04/21/2026 04:15:08 AM
- Form POS AM - Post-Effective amendments for registration statement • Edgar (US Regulatory) • 04/16/2026 09:25:30 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 04/07/2026 04:30:50 PM
- Form NT 10-K - Notification of inability to timely file Form 10-K 405, 10-K, 10-KSB 405, 10-KSB, 10-KT, or 10-KT405 • Edgar (US Regulatory) • 03/31/2026 09:04:37 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 01/15/2026 10:06:20 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 01/02/2026 10:14:59 PM
- Form DEF 14A - Other definitive proxy statements • Edgar (US Regulatory) • 11/28/2025 09:43:27 PM
- Form 424B5 - Prospectus [Rule 424(b)(5)] • Edgar (US Regulatory) • 11/25/2025 10:23:07 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 11/20/2025 09:26:03 PM
- Form PRE 14A - Other preliminary proxy statements • Edgar (US Regulatory) • 11/19/2025 09:15:48 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 11/14/2025 09:44:21 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/31/2025 04:29:10 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/30/2025 08:40:05 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/24/2025 04:28:38 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/14/2025 06:22:26 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 08/14/2025 09:00:38 PM
- Form 424B5 - Prospectus [Rule 424(b)(5)] • Edgar (US Regulatory) • 07/01/2025 09:04:38 PM
