Wednesday, November 05, 2025 11:08:43 AM
I've been done defending the company for a while but I feel it necessary to say their decision to target a heavily pretreated population is relatively sound.
Obviously we would all like them to have a first line therapy but the reality is that will never happen. There is a reason radiation therapy is the first choice. With other approved therapies available further down the treatment line the odds of unseating them would be low for any company as any new therapy would need to provide a much greater benefit than the current standard of care. Going after a patient population, in Marker's case, CAR-T relapsed or refractory patients, significantly increase their odds at approval as these patients do not have any available treatment options so the bar for approval is a lot lower.
Either way the company has still yet to prove they can execute any strategy so until that starts to change we are pretty much dead in the water. As it stands, Rose is still holding strong and clinging to anything she can grab hold of. ;)
Obviously we would all like them to have a first line therapy but the reality is that will never happen. There is a reason radiation therapy is the first choice. With other approved therapies available further down the treatment line the odds of unseating them would be low for any company as any new therapy would need to provide a much greater benefit than the current standard of care. Going after a patient population, in Marker's case, CAR-T relapsed or refractory patients, significantly increase their odds at approval as these patients do not have any available treatment options so the bar for approval is a lot lower.
Either way the company has still yet to prove they can execute any strategy so until that starts to change we are pretty much dead in the water. As it stands, Rose is still holding strong and clinging to anything she can grab hold of. ;)
My DD is not a substitute for your DD
Recent MRKR News
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 05/15/2026 09:00:38 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 05/04/2026 08:30:23 PM
- Form DEFA14A - Additional definitive proxy soliciting materials and Rule 14(a)(12) material • Edgar (US Regulatory) • 03/20/2026 08:08:49 PM
- Form ARS - Annual Report to Security Holders • Edgar (US Regulatory) • 03/20/2026 08:07:05 PM
- Form DEF 14A - Other definitive proxy statements • Edgar (US Regulatory) • 03/20/2026 08:05:49 PM
- Marker Therapeutics Reports Year-End 2025 Corporate and Financial Results • GlobeNewswire Inc. • 03/18/2026 09:31:30 PM
- Marker Therapeutics to Present at the Oppenheimer 36th Annual Healthcare Life Sciences Conference • GlobeNewswire Inc. • 02/18/2026 01:00:00 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 02/09/2026 09:06:45 PM
- Good Morning America Features Baylor College of Medicine Pancreatic Cancer Study Utilizing Marker Therapeutics’ MAR-T Cell Technology • GlobeNewswire Inc. • 01/26/2026 12:00:00 PM
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- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 11/19/2025 09:10:21 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 11/19/2025 09:01:15 PM
- Form SCHEDULE 13D/A - General Statement of Acquisition of Beneficial Ownership: [Amend] • Edgar (US Regulatory) • 11/17/2025 09:22:54 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 11/14/2025 12:20:47 PM
- Marker Therapeutics Reports Third Quarter 2025 Financial Results and Provides Business Updates • GlobeNewswire Inc. • 11/14/2025 12:00:00 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 11/13/2025 10:29:46 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 11/05/2025 12:36:59 PM
- Marker Therapeutics appoints Kathryn Penkus Corzo to Board of Directors • GlobeNewswire Inc. • 11/05/2025 12:30:00 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 11/04/2025 10:09:13 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 11/04/2025 10:03:27 PM
- Form 3 - Initial statement of beneficial ownership of securities • Edgar (US Regulatory) • 11/04/2025 09:54:39 PM
- Marker Therapeutics Announces Upcoming Presentations on MT-601 in Relapsed Non-Hodgkin and Hodgkin Lymphoma at the 67th ASH Annual Meeting • GlobeNewswire Inc. • 11/03/2025 02:15:00 PM
- Marker Therapeutics Announces First Patient Treated in Off-the-Shelf Program • GlobeNewswire Inc. • 10/06/2025 11:30:59 AM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/06/2025 11:30:37 AM
