Wednesday, November 05, 2025 7:10:04 AM
There is no obligation for any patient to have a particular treatment if they decide not to have it. If a patient, in full knowledge of the facts, decided that they did not want to have, say, the temozolomide because they knew it suppresses T-cell function and may, therefore, decrease the efficacy of DCVax-L, I doubt very much that they would be disqualified from having the DCVax-L on the NHS, especially if it saved the NHS money by not having to prescribe temozolomide (over £4k/month).
I think that politically it would be very unlikely for patients to be denied a life-saving treatment (or having to "go privately") to have that treatment because one of the components of the S.O.C. is a known suppressor of that new treatment which is the most effective component of the "new" SOC.
Why do you think that patients in the placebo-arm who relapsed in the trial and then received DCVax-L much later than those in the active-arm group, did better? They were not receiving temozolomide when given DCVax-L.
I think that politically it would be very unlikely for patients to be denied a life-saving treatment (or having to "go privately") to have that treatment because one of the components of the S.O.C. is a known suppressor of that new treatment which is the most effective component of the "new" SOC.
Why do you think that patients in the placebo-arm who relapsed in the trial and then received DCVax-L much later than those in the active-arm group, did better? They were not receiving temozolomide when given DCVax-L.
Recent NWBO News
- Form 8-K - Current report • Edgar (US Regulatory) • 04/07/2026 04:30:50 PM
- Form NT 10-K - Notification of inability to timely file Form 10-K 405, 10-K, 10-KSB 405, 10-KSB, 10-KT, or 10-KT405 • Edgar (US Regulatory) • 03/31/2026 09:04:37 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 01/15/2026 10:06:20 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 01/02/2026 10:14:59 PM
- Form DEF 14A - Other definitive proxy statements • Edgar (US Regulatory) • 11/28/2025 09:43:27 PM
- Form EFFECT - Notice of Effectiveness • Edgar (US Regulatory) • 11/26/2025 05:15:34 AM
- Form 424B5 - Prospectus [Rule 424(b)(5)] • Edgar (US Regulatory) • 11/25/2025 10:23:07 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 11/20/2025 09:26:03 PM
- Form PRE 14A - Other preliminary proxy statements • Edgar (US Regulatory) • 11/19/2025 09:15:48 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 11/14/2025 09:44:21 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/31/2025 04:29:10 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/30/2025 08:40:05 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/24/2025 04:28:38 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/14/2025 06:22:26 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 08/14/2025 09:00:38 PM
- Form 424B5 - Prospectus [Rule 424(b)(5)] • Edgar (US Regulatory) • 07/01/2025 09:04:38 PM
