Sunday, October 05, 2025 10:53:02 AM
Boi,
I like your analysis, but I have a couple of disagreements.
1. While the 50/50 partnership split might be feasible in EU, it is likely to be closer to 35-40% for Avxl in the US.
2. I think that $20k a year per patient in Europe will be be far too high, I’m thinking closer to $12k. This allows broader penetration with government coverage. In the US I can see a higher price in the $18-$20k range, as well as parts of Asia & Middle East.
3. While Anavex may be worth $60B in 3-5 yrs, that is going to be a high number for someone to acquire, can they recoup that investment before the patents expire or other competitive products are approved? AvXl may just stay independent at that point.
All of this doesn’t take into consideration 3-71 potential, which is still too early to include in any calculation.
I don’t think we ever get to those lofty MC’s estimates, I believe the company will be acquired in the $15B to $20B range in 2027. That has always been Missling’s goal, never to be a stand alone company once marketed products were a realization.
Karuna was bought for around $14B ($1.5B of that was debt) so $20B sounds reasonable to me for Blarcamesine. Nobody is buying us for $60B+, that is just pie in the sky hope. BP doesn’t typically spend that kind of money on acquisitions UNLESS it is a mega merger, just too much risk for them.
$20B buyout with 95M shares is about $210.
I like your analysis, but I have a couple of disagreements.
1. While the 50/50 partnership split might be feasible in EU, it is likely to be closer to 35-40% for Avxl in the US.
2. I think that $20k a year per patient in Europe will be be far too high, I’m thinking closer to $12k. This allows broader penetration with government coverage. In the US I can see a higher price in the $18-$20k range, as well as parts of Asia & Middle East.
3. While Anavex may be worth $60B in 3-5 yrs, that is going to be a high number for someone to acquire, can they recoup that investment before the patents expire or other competitive products are approved? AvXl may just stay independent at that point.
All of this doesn’t take into consideration 3-71 potential, which is still too early to include in any calculation.
I don’t think we ever get to those lofty MC’s estimates, I believe the company will be acquired in the $15B to $20B range in 2027. That has always been Missling’s goal, never to be a stand alone company once marketed products were a realization.
Karuna was bought for around $14B ($1.5B of that was debt) so $20B sounds reasonable to me for Blarcamesine. Nobody is buying us for $60B+, that is just pie in the sky hope. BP doesn’t typically spend that kind of money on acquisitions UNLESS it is a mega merger, just too much risk for them.
$20B buyout with 95M shares is about $210.
Recent AVXL News
- Form 8-K - Current report • Edgar (US Regulatory) • 05/22/2026 12:15:26 PM
- Anavex Life Sciences Receives Expected Nasdaq Delinquency Notification • GlobeNewswire Inc. • 05/22/2026 12:00:00 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 05/15/2026 08:15:25 PM
- Form 3 - Initial statement of beneficial ownership of securities • Edgar (US Regulatory) • 05/14/2026 08:15:30 PM
- Form NT 10-Q - Notification of inability to timely file Form 10-Q or 10-QSB • Edgar (US Regulatory) • 05/11/2026 08:30:22 PM
- CEO Transition and Delayed SEC Filing Put Anavex (AVXL) Leadership Changes in Focus • IH Market News • 05/06/2026 02:52:36 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 05/06/2026 11:04:59 AM
- Anavex Life Sciences Board of Directors Appoints Former Senior Vice President of Clinical Development Terrie Kellmeyer, PhD, as Interim Chief Executive Officer • GlobeNewswire Inc. • 05/06/2026 11:00:00 AM
- Form 3 - Initial statement of beneficial ownership of securities • Edgar (US Regulatory) • 05/01/2026 11:18:47 PM
- Anavex Life Sciences Highlights New Scientific Findings on Shared Biology Between Autism and Alzheimer’s Disease • GlobeNewswire Inc. • 04/14/2026 11:30:00 AM
- Anavex Life Sciences to Present at the 25th Annual Needham Virtual Healthcare Conference • GlobeNewswire Inc. • 04/07/2026 11:30:00 AM
- Anavex withdraws EU approval filing for Alzheimer’s therapy • IH Market News • 03/30/2026 12:39:26 PM
- Anavex Life Sciences Provides Comprehensive Regulatory Update • GlobeNewswire Inc. • 03/30/2026 11:30:00 AM
- Form 8-K - Current report • Edgar (US Regulatory) • 03/25/2026 08:06:00 PM
- Anavex withdraws EU marketing application for Alzheimer’s therapy blarcamesine • IH Market News • 03/25/2026 02:06:58 PM
- Anavex Life Sciences Provides Update on Regulatory Review in the EU for Blarcamesine to Treat Early Alzheimer’s Disease • GlobeNewswire Inc. • 03/25/2026 11:30:00 AM
- Anavex Life Sciences Presents New Data from its AD-004 Phase IIb/III Trial at AD/PD 2026 Conference Demonstrating Consistent Correlation Between the Treatment Effect of Oral Blarcamesine and Preservation of Brain Volume in Early Alzheimer’s Disease • GlobeNewswire Inc. • 03/23/2026 11:30:00 AM
- New Scientific Findings Highlight Hypothesis of Autophagy Failure as a Precursor of Amyloid Beta and Tau Pathology in Alzheimer’s Disease • GlobeNewswire Inc. • 03/20/2026 11:30:00 AM
- Anavex Life Sciences Presents Significant Treatment Effects of Blarcamesine in New Advanced Alpha-Synuclein Model of Parkinson’s Disease at AD/PD 2026 Conference • GlobeNewswire Inc. • 03/17/2026 11:30:00 AM
- Anavex Life Sciences to Present at the Citizens Life Sciences Conference • GlobeNewswire Inc. • 03/03/2026 12:30:00 PM
- Anavex Life Sciences to Present at the 46th TD Cowen Annual Health Care Conference • GlobeNewswire Inc. • 02/25/2026 12:30:00 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 02/25/2026 11:07:01 AM
- Anavex Life Sciences Appoints Seasoned Healthcare Leader to Board of Directors • GlobeNewswire Inc. • 02/23/2026 12:30:00 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 02/09/2026 09:40:27 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 02/09/2026 12:31:17 PM
