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Re: QL300 post# 787330

Tuesday, 09/09/2025 2:07:17 PM

Tuesday, September 09, 2025 2:07:17 PM

Post# of 822231
NOPE!

Several changes have been made over the years (replacement of a randomized design with a synthetic control arm, removal of PFS as the primary endpoint, addition of a new study population, conduct of unplanned analyses), raising many questions about data interpretability


To confirm the results of DCVax-L, it would be ideal to design two new trials, one in the newly diagnosed GB setting and another in the relapsed-disease setting, both randomized, for comparison with the standard of care

Conflicts of Interest
The authors declare no conflict of interest.


https://pmc.ncbi.nlm.nih.gov/articles/PMC10296384/


Here's another --- https://www.sciencedirect.com/science/article/pii/S0035378723009190https://pmc.ncbi.nlm.nih.gov/articles/PMC10296384/
"Disclosure of interest
T.O. declares that he has no competing interest."
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