Sunday, June 29, 2025 4:02:21 PM
1️⃣ The External Control Arm (ECA) in the $NWBO trial was not based on real-world data, electronic health records, or historical placebo groups.
Instead, it was constructed from patient-level, peer-reviewed data drawn from contemporaneous, randomized controlled trials (RCTs) of standard of care for glioblastoma. That’s precisely what the JAMA Oncology paper states:
“The comparator cohort was constructed from individual patient-level data derived from contemporaneous, randomized, controlled clinical trials.”
📌 Yes, individual patient-level data was used, not summary statistics, not “lego-style dots,” but actual de-identified data shared by academic collaborators. Read the supplementary materials. This is peer-reviewed science, not propaganda.
2️⃣ Innovation Passport (IP) The MHRA did grant one. It’s listed in the UK’s Innovative Licensing and Access Pathway (ILAP) records under the formal designation for Dendritic Cell Vaccines for Glioblastoma, with Northwest Biotherapeutics as sponsor.
It wasn’t “shouted out” because the IP is an intermediate regulatory step, not a marketing point. But it’s absolutely public and verifiable via the MHRA, NICE, and UK Government databases.
3️⃣ Why lie if the story’s so good?
That’s a question for you and your crew. Here’s what’s not being shouted but should be:
✅ DCVax-L showed a median survival of 22.4 months in newly diagnosed GBM, compared to ~15-17 months in RCT controls with a long tail of survivors.
✅ It’s the first Phase 3 glioblastoma trial in decades to report improved overall survival in both newly diagnosed and recurrent settings with no serious safety issues.
✅ It’s now part of MHRA’s new PICV approval framework, designed for personalized cancer vaccines.
And while the stock is manipulated, the data is not.
So let’s reframe your question:
“Why the attacks, the lies, and the desperate FUD if the science wasn’t real?”
Because it is real. And you know it.
Recent NWBO News
- Form 8-K - Current report • Edgar (US Regulatory) • 01/15/2026 10:06:20 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 01/02/2026 10:14:59 PM
- Form DEF 14A - Other definitive proxy statements • Edgar (US Regulatory) • 11/28/2025 09:43:27 PM
- Form EFFECT - Notice of Effectiveness • Edgar (US Regulatory) • 11/26/2025 05:15:34 AM
- Form 424B5 - Prospectus [Rule 424(b)(5)] • Edgar (US Regulatory) • 11/25/2025 10:23:07 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 11/20/2025 09:26:03 PM
- Form PRE 14A - Other preliminary proxy statements • Edgar (US Regulatory) • 11/19/2025 09:15:48 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 11/14/2025 09:44:21 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/31/2025 04:29:10 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/30/2025 08:40:05 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/24/2025 04:28:38 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/14/2025 06:22:26 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 08/14/2025 09:00:38 PM
- Form 424B5 - Prospectus [Rule 424(b)(5)] • Edgar (US Regulatory) • 07/01/2025 09:04:38 PM
- Form 10-K - Annual report [Section 13 and 15(d), not S-K Item 405] • Edgar (US Regulatory) • 03/31/2025 09:23:24 PM
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