Iron Mike, it may be clear that when Sawston is built out it will be able to supply all UK demands and perhaps even all of Europe, but it's clear that the company is looking for additional sites elsewhere in the world, they've said so in their financials.
I believe it's clear they're not looking for tiny cleanrooms to manually make DCVax-L, they're looking for larger cleanrooms with adequate capacity to take multiple EDEN units that also have the capability of properly handling all aspects of making, storing and distributing the vaccine.
It's my believe that such capability exists in many places throughout the world. In some cases it may be for just a few EDEN units, in other places hundreds of even thousands of units. The point is that multiple such facilities will work until such time as the supply is completely in line with the demand.
I don't know how many brain surgeries are done in LA in a year, but I don't believe that it's more than a few hundred a year. I would suspect that UCLA, or City of Hope, or others in LA could handle perhaps 10 units, each capable of 50 batches of vaccine, or 500 batches a year. Probably all that's needed for the Greater LA area for brain cancers alone. Of course, if the vaccine is labeled tumor agnostic, then the numbers would need to increase dramatically. I don't believe it would be a problem within all the fine medical facilities located in the greater LA area.
I wouldn't be surprised to find that nearly every facility equipped to do brain surgery may have all the capabilities needed to make the vaccine.
Gary
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