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Re: hyperopia post# 770781

Saturday, 06/07/2025 2:58:53 PM

Saturday, June 07, 2025 2:58:53 PM

Post# of 824189
I agree that the patent looks like it matches the 2024 mods that were adding extra functionality. But that is not the design they are going forward with because they decided it was too large.

Per the 10K:

During 2024, the Company’s Flaskworks subsidiary and a specialized contractor developed a GMP-compatible prototype of the Flaskworks system for a “closed” manufacturing process for DCVax-L. Another prototype, with smaller dimensions, had been developed in 2023. The Company has determined that the smaller prototype will be preferable, to enable more units to fit in each manufacturing lab. Production of the GMP-grade units will be timed to coincide with the timing for buildout of Grade C labs in the Sawston facility. When the GMP-grade units are delivered, Advent BioServices will undertake qualification and validation of those units, conduct engineering runs and collect data, and apply to regulators for approval to use the system to produce DCVax-L for patients. As previously reported, the Company views the Flaskworks program and system as a centerpiece of efforts toward scale-up for potential commercial operations.



BTW, I take the NWBO explanation in the 10K with a grain of salt.
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