NorthWest Biotherapeutics Inc (NWBO)

[biosectinvestor]

I agree. I believe they are working likely to validate with as close to approval as possible. That is usually the most optimal time. A lot of these newer drugs are made by hand in labs for the early trials. Creating a full, automated, commercial facility long before a product is even applied for for approval, is the road to technological death for the most innovative and small bios with the newest ideas and technologies. Of course for Big Pharma, they can do whatever they want. But the FDA killed many early, small bios, decades ago, by forcing them to have full, commercial operations BEFORE their trials even started, at the beginning of this technology. They thought, the end product, in order to be validated, had to be made in the EXACT conditions of a full factory for commercial production, to validate from Phase 1. They killed off many companies and prevented much research. They just did not know any better. They had a hand on the science, but failed to grasp the commercial impossibility they were creating. So it is expected that manufacturing will be part of that process and scale up into the approval and after the approval process, and that's why it happens best at this time, not before, not earlier, because then you have a fallow factory, that you have to maintain in pristine shape and ready to go, when you're not producing any product and there is zero revenue. That is very costly. But the shorts would have you believe that they haven't even started or thought of it yet. The cost for the new clean rooms is lower. The tech is more cost efficient. It has not been some prohibitive, massive investment of billions of dollars to get to this stage and the shorts would of course, speculatively lay it all on thick, make comparisons with other technologies without any thoughtful comparison, and make people fear. Now, that's not to say that market forces will immediately change, or that they won't need to raise funds to scale up if no deal materializes to make it much easier. But the fact is, the shorts know far less than they think they do and they make their money by always predicting the worst, worst case and making it seem as if it is the most likely and most practical reality. That's easy money for them.

Great post TheFollower.