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skitahoe

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skitahoe

Re: ATLnsider post# 758766

Thursday, 04/03/2025 9:15:46 PM

Thursday, April 03, 2025 9:15:46 PM

Post# of 821065
When the trial began, the cross over was mandated, but after pseudoprogression was clear, the trial had to  be modified or abandoned.  Fortunately all four regulatorsop agreed on how the trial could continue. 
I don't know that today a new trial could be conducted with a PFS goal and be able to differentiate between progression and pseudoprogression.
Gary 
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