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Thursday, 02/06/2025 11:39:13 AM

Thursday, February 06, 2025 11:39:13 AM

Post# of 821480
We haven't talked about this much here today, but maybe you pumpers can help me out with this one.

The biggest X buzz right now is around Minister Andrew Gwynne and his statements yesterday regarding brain tumors.

Specifically, he said that brain tumors are an area where things "have not progressed at all".

Now, I think that DCVax-L will get UK approval. But in my opinion this statement is being glanced over with a little too much indifference. The X crowd is saying things like "he needs to look into DCVax! Is he aware that Northwest is working on this in his own country? A drug called DCVax has been under review by the MHRA for over a year!" I find it almost impossible to believe, though, that he doesn't know about DCVax-L.

Is it not concerning that with the MAA over a year into review, likely having been through two CHM discussions, and on the doorstep of a decision, the PUS at the Department of Health and Social Care who almost certainly has been made aware of this application by now has just stated brain tumor treatment is an area that "has not progressed at all"? That just seems like an odd choice of words for someone that would very much have their finger on the pulse better than most regarding the DCVax MAA.

Now, he also platformed brain tumors as being "an integral part of our cancer plan" so maybe he was politicking up his success a bit. i.e. painting a picture of how dire the treatment of brain tumors is, how important advancements will be to their cancer plan, while knowing that he is going to have a big brain cancer win to tout just around the corner. It certainly could be that angle.

But the very direct choice of "has not progressed at all" seems a bit too dire and unnerving. I would think that he would use a tone more along the lines of "It's been a long time since we've made an advancement in this area, but we are optimistic that we can make progress". Am I picking up the wrong vibes from this?

"Brain tumor care has not advanced at all...............psyche! Here's a new drug approval!"
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