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Re: Investor2014 post# 481380

Thursday, 01/23/2025 8:10:37 PM

Thursday, January 23, 2025 8:10:37 PM

Post# of 518966

We never initially were provided with the ADL result and instead some Odds Ratio meaningless nonsense that the company has now abandoned and rightly so accepted that ADL was not significant.



You still want to make this about what AVXL did? The FDA's guidance to use ADL as an endpoint, is odds ratio's nonsensical equal. It should not have been in an early AD trial, as the likelihood that there would be changes in either the drug or placebo group, were too low. The only reason it is a topic, is because the guidance hasn't changed yet. It is the FDA on a learning curve. That change will happen, among other changes, of this I am mostly certain. Investors are good at reading tea leaves, especially the obvious ones.

This is an early AD drug candidate. We know because it has been repeatedly amplified.
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