Sunday, January 05, 2025 5:33:56 PM
Why do you think I said 'in it's forthcoming combination forms'?
Because in it's forthcoming combinations with Poly-ICLC alone it will render the existing SOC completely redundant. The only thing that will remain from the existing SOC will be the resection and I am willing to bet that by 2028-2030 DCVax-Direct will be replacing at least some resections for less complicated/ early onset GBMs and Gliomas.
Now add in forthcoming (2027-8) off-label (cheap) PD-1 inhibitors and CSFR-1 inhibitors like PLX3397 (Pexidartinib) and you have a treatment that - end-to-end - is still going to be considerably cheaper for anyone involved in footing the bill, not to mention orders of magnitude more efficacious!
If I were a patient with the choice of being fried by radiation & poisoned by chemo or being given a immunotherapeutic cocktail of my own supercharged cells back to me with a vastly lower toxicity profile, a considerably better expected QOL, and much higher chance of survival I would knock down every fuckin door in sight to get the latter! Patient advocacy groups will be doing exactly that!
Because in it's forthcoming combinations with Poly-ICLC alone it will render the existing SOC completely redundant. The only thing that will remain from the existing SOC will be the resection and I am willing to bet that by 2028-2030 DCVax-Direct will be replacing at least some resections for less complicated/ early onset GBMs and Gliomas.
Now add in forthcoming (2027-8) off-label (cheap) PD-1 inhibitors and CSFR-1 inhibitors like PLX3397 (Pexidartinib) and you have a treatment that - end-to-end - is still going to be considerably cheaper for anyone involved in footing the bill, not to mention orders of magnitude more efficacious!
If I were a patient with the choice of being fried by radiation & poisoned by chemo or being given a immunotherapeutic cocktail of my own supercharged cells back to me with a vastly lower toxicity profile, a considerably better expected QOL, and much higher chance of survival I would knock down every fuckin door in sight to get the latter! Patient advocacy groups will be doing exactly that!
Recent NWBO News
- Northwest Biotherapeutics Announces Establishment Of the Company's Own Dedicated Leukapheresis Clinic • PR Newswire (US) • 04/21/2026 01:30:00 PM
- Northwest Biotherapeutics Announces Establishment Of the Company's Own Dedicated Leukapheresis Clinic • PR Newswire (US) • 04/21/2026 01:30:00 PM
- Form EFFECT - Notice of Effectiveness • Edgar (US Regulatory) • 04/21/2026 04:15:08 AM
- Form POS AM - Post-Effective amendments for registration statement • Edgar (US Regulatory) • 04/16/2026 09:25:30 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 04/07/2026 04:30:50 PM
- Form NT 10-K - Notification of inability to timely file Form 10-K 405, 10-K, 10-KSB 405, 10-KSB, 10-KT, or 10-KT405 • Edgar (US Regulatory) • 03/31/2026 09:04:37 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 01/15/2026 10:06:20 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 01/02/2026 10:14:59 PM
- Form DEF 14A - Other definitive proxy statements • Edgar (US Regulatory) • 11/28/2025 09:43:27 PM
- Form 424B5 - Prospectus [Rule 424(b)(5)] • Edgar (US Regulatory) • 11/25/2025 10:23:07 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 11/20/2025 09:26:03 PM
- Form PRE 14A - Other preliminary proxy statements • Edgar (US Regulatory) • 11/19/2025 09:15:48 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 11/14/2025 09:44:21 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/31/2025 04:29:10 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/30/2025 08:40:05 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/24/2025 04:28:38 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/14/2025 06:22:26 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 08/14/2025 09:00:38 PM
- Form 424B5 - Prospectus [Rule 424(b)(5)] • Edgar (US Regulatory) • 07/01/2025 09:04:38 PM
