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Re: Doc328 post# 472439

Tuesday, 10/29/2024 9:15:18 PM

Tuesday, October 29, 2024 9:15:18 PM

Post# of 517536
@Doc, What are you hoping to see from Dr. Sabbagh's presentation? Beyond safety and tolerability, there are a few impactful factors for MAA success, like the efficacy of the S1WT subgroup and OLE 96-week data. Would the SS sig outcome of both primary endpoints of either the S1WT subgroup or OLE change your approval outlook? The S1 activation/correlation and DNA details seem less relevant in the submission.
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