Sunday, October 06, 2024 7:29:56 PM
I skimmed the linked document and see that this other DC platform technology is attempting to address cancers and viruses, thus supporting the development of dcvax being able to address the same.
Imo dcvax should be the more effective platform than those that target a more limited subset of enemy antigens, since dcvax DCs present as many antigens as possible for the DCs to pick up from the lysate.
That’s why dcvax L has been the most successful against gbm, because the informed immune response is against hundreds of antigens and gbm is very diverse to begin with and highly mutational. In fact dcvax works better against “hot” tumors than less “hot” tumors.
In summary, yes there is potential for dcvax cancers, viruses, and possibly more!!!
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