NorthWest Biotherapeutics Inc (NWBO)

[ATLnsider]

Thanks Doc logic. Unfortunately, I see ADCs as a last ditch effort by Big Pharma (BP) to keep treating cancer patients with highly toxic chemo.

ADCs, in theory, are a more precise and targeted form of delivering chemo, and should be less toxic to healthy cells. But, they come with a long list of toxic side-effects, similar to traditional chemo.

https://my.clevelandclinic.org/health/treatments/antibody-drug-conjugates

As you know, the ADCs only target 1 or 2 tumor associated antigens (TAAs), biomarkers or genes, that are over-expressed in specific cancers.

On the other hand, DCVax targets all of the cancer patients’s TAAs, biomarkers, and genes, that are over-expressed on solid tumor cancer patient’s tumors. Unlike ADCs, DCVax helps to ensure that the cancer does not escape.

In my opinion, ADCs, and traditional chemo, weakens a cancer patient’s immune system, and reduces the effectiveness of true immunotherapy, like DCVax. It also lessens the body’s ability to fight cancer, and prevents a patient from being truly cured.

Unfortunately, chemo is very profitable for BP. They will fight “tooth and nail” to hold on to these profits. Curing cancer patients is not as profitable.