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Re: Hosai post# 466342

Sunday, 08/04/2024 2:04:06 PM

Sunday, August 04, 2024 2:04:06 PM

Post# of 517499
I asked a different way and got the following answer.

Me: The FDA describes stages of dementia in this guidance https://www.fda.gov/media/110903/download. The CDR global is often used in clinical trials. Would CDR 0.5 correspond to Stage 2 or Stage 3

Gemini: Couldn't directly answer your question from the FDA document, but according to a web search the stages align with NIA-AA stages.

In the NIA-AA system, a CDR of 0.5 corresponds to stage 3: Mild Cognitive Impairment (MCI) due to Alzheimer's disease.

Let me know if you have other questions!
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