Saturday, June 15, 2024 5:43:45 PM
You have to know little about what you are playing if you don't want to end up with losing or being broke. Do you see the following symbols? Do you know what they are? These are just some examples of tumor-associated peptides bonded with MHC Class 1&2 molecules on dendrtic cell surface. These are the target information that t-cells are going to use to hunt down cancer cells. You can simply grab one and google it to see if researcher have talked about those peptides. If not, that means they were not found before NWBO found them. Do you know the significance of these findings?
Those peptides presented at last year ASCO, especially those that only exists in cancer cells and are absent from normal cells are diamonds. Many neo-peptide cancer vaccine companies are dreaming to own them. Keep in mind far less 1% of neo-peptide can trigger anti-tumor immune response. The ones dendritic cells present to t cells will certain trigger t cells to kill cancer cells.
Finding neo-peptide that can trigger immune response is exactly the reason that Moderna has a partnership with Immatics. I strongly suggest you read the Immatics webpage about how t-cells can attack t-cells.
https://investors.modernatx.com/news/news-details/2023/Moderna-and-Immatics-Announce-Strategic-Multi-Platform-Collaboration-to-Develop-Innovative-Oncology-Therapeutics/default.aspx
https://immatics.com/t-cells-and-solid-tumors/
The following figure is the FDA approved ADCs. ADCs are not something new. It is only in the last a couple of years that BPs rekindle their interest in ADCs. As a matter of fact, the timeline should be after the data lock of the p3 trial. Have you seen AZN is going to invest $1.5b to manufacture ADCs? All the BPs have their ADC programs now. ADCs are bio missiles. To hit target accurately while keeping intact normal tissues, those ADCs need precise target information. Guess which platform can provide the precise target information? DCVax-L. If you have any doubt, find the encoded genes related to each of the approved ADCs, search in the data Dr. Liau uploaded, and check the variation of those overexpressed mutations before and after DCVax-L + poly-iclc treatment.
As today, even without any approval, simply using DCVax-L platform to supply neo-peptides and targets for ADCs, LP can make NWBO have a market cap of billions of dollars.
Now do you still think I should worry about being broke?
https://www.nature.com/articles/s41587-024-02168-5
Recent NWBO News
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