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Re: XMaster2023 post# 698636

Saturday, 06/15/2024 2:54:58 PM

Saturday, June 15, 2024 2:54:58 PM

Post# of 705918

The people that understand what agnostic means are fully invested because they understand the science and the investment.


One can read the FDA guidance on tissue agnostic and see how it does not apply to DCVax-L.

For the purpose of this guidance, the term tissue agnostic oncology drug refers to a drug that targets a specific molecular alteration(s)3 (a kind of biomarker) across multiple cancer types as defined, for example by organ, tissue, or tumor type.

Not complicated here. Anybody with a basic clue on the science can see this does not talk about DCVax-L.

Further, one might listen to LL. She says repeatedly how unique tumor micromanagement in GBM is a reason why DCvax-L works. Again, the exact opposite of tissue agnostic.
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