NorthWest Biotherapeutics Inc (NWBO)

[HappyLibrarian]

To address the overall thrust of your questions many disruptive technologies advanced by small players get ignored by established players, especially if they do not fit into their business model.

DCVax-L and Direct are disruptive technologies that do not fit into Big Pharma’s business model or even the business model of hospitals and oncologists (though this to a lesser degree). Direct could even disrupt not just chemo and radiation but down the road could also reduce reliance on surgery if used as an alternative for operative tumors (right now it’s intended for inoperable).

For one example, look at the fact Blockbuster turned down the chance to buy Netflix in its infancy. Where is Blockbuster now?