Monday, January 22, 2024 3:22:46 PM
I just want to make one more point on the Elios tlpo versus tlpodc phase ii disease free melanoma trial and show you how they are working like Novocure does. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401209/
Look at the link/figure below. Now realize that based upon this, they’re currently saying, well since tlpo and tlpodc are essentially equal, we should do a phase iii on tlpo because we can’t really afford to keep trialing tlpodc.
But wait a minute, look at cases at risk at thirty and 36 months.🤨 By 36 months, which is what they go by in their trial “survival section,” only one, that’s right, one data point was used to get their survival number for tlpo.😬 But look, they matured the tlpodc group and let 19 cases be at risk for the 36 month analysis.
You see what they did there? They didn’t bother to build a DC manufacturing base like NWBO, so apparently they said fck it, let’s just get one good 36 month data point and call it a day, so that we don’t have to build up an industry. (They also only had six tlpo data points at 30 months)
(Note: remember the Elios (Orbus Therapeutic’s parent) trial was for melanoma)
https://www.ncbi.nlm.nih.gov/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Click%20on%20image%20to%20zoom&p=PMC3&id=10401209_jitc-2023-006665f02.
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