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Re: supersteve13 post# 643225

Thursday, 10/26/2023 2:37:05 PM

Thursday, October 26, 2023 2:37:05 PM

Post# of 823222
The primary endpoint of NVCR's EF-11 trial was PFS. For the rGBM setting the FDA has been allowing that endpoint. It was clearly met so the trial was a success.

One can fairly argue that PFS w/o OS is questionable, but that is up to regulators to decide.

For nGBM, where NWBO is, the NVCR EF-14 trial was highly stat sig for OS between the trial arms despite crossover.
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