Netramark Holdings Inc (AINMF)

[BlairWill]

The AI Company that Will Make Money - Leveraging Large Language Models with NetraAI for Clinical Trial De-Risking: Launching NetraGPT

Joseph Geraci, PhD, CTO/CSO, Bessi Qorri, PhD, Scientific Communications Manager, & Luca Pani, MD, Chief Innovation and Regulatory Officer

NetraAI represents a distinctive, Good Clinical Practice (GCP)-authenticated machine learning architecture that offers an accessible interface for researchers to engage with consolidated multimodal datasets. This empowers sponsors to uncover explainable patient subgroups pertaining to efficacy, toxicity, and placebo response across an array of therapeutic domains, such as oncology, psychiatric disorders, neurodegenerative disorders, and rare diseases. The innovative NetraMark algorithms enable the employment of Large Language Models (LLMs), including the likes of ChatGPT, to absorb the potent hypotheses generated by the NetraAI platform from sponsor provided clinical trial patient populations, thereby enhancing the articulation of findings with increased explainability and context. NetraAI essentially functions as a data microscope, amplifying vital patient population data, and enabling new discoveries.

https://www.netramark.com/netragpt-white-paper
The true strength of the NetraAI architecture stems from its capability to discern distinct combinations of variables defining patient subpopulations, in correlation to drug or placebo response and adverse reactions—elements of key importance in clinical trials. The output of NetraAI comprises hypotheses embodied as a collection of variables and subpopulations, bolstering biostatistics, as well as supplying data to train universally applicable models. We have crafted a system whereby the output from NetraAI is fed into generative pre-trained (GPT) models using LLM APIs. Specifically, the integration of the ChatGPT API with NetraAI amplifies our capacity to generate reports that deliver clear, succinct insights to sponsors, thereby facilitating informed decision-making for their clinical trials. This novel NetraGPT module is in alignment with our mission to offer augmented intelligence algorithms capable of learning from clinical trial data, in the face of inherent challenges related to these smaller and diverse datasets.