OTOH, these could wind up being another Fen-Phen when all the large-scale long-term usage adverse event stats are analyzed. Or another amphetamines (1960s) good, ole 2,4-dinitrophenol (DNP) (1930s) https://www.dazeddigital.com/beauty/article/58533/1/brief-history-diet-pills-weight-loss-drugs-ozempic-obetrol-fenphen-benzedrine https://pubmed.ncbi.nlm.nih.gov/27916644/ Or diet equivalents of the non-diet drugs: diethylstilbestrol (DES) - marketed for 37 years thalidomide. We ought tread carefully with new classes of drugs, most axespeshully for off-label uses...