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Re: HyGro post# 591248

Friday, 05/05/2023 10:02:10 PM

Friday, May 05, 2023 10:02:10 PM

Post# of 826158
Who cares is correct.

Per your comments
"Who cares. What matters is NWBO designated PFS as their primary endpoint and the trial FAILED to meet the endpoint and they tossed it out. Dr. Liau designated PFS as the top efficacy measure in her Keytruda combo trial, so the argument that DCVax-L causes pseudo-PFS seems specious or she certainly wouldn't use it. Previous GBM trials have shown many treatments also can cause pseudo PFS but PFS is a commonly used metric. Again just look at Dr. Liau's protocol.

Tossing out primary endpoint that failed when a trial is virtually complete is very suspect for ANY trial. Ya think the FDA has seen every failed trial be spun into something that looks good. They will not look kindly on NWBO's protocol spin."

The fact remains that the OS data results outperformed the PFS, "The statistical guess factor results."
You already know this, but it is worth repeating. The OS data is the gold standard and that is the bottom-line FACT.
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