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Thursday, February 23, 2023 10:29:51 AM
Let's just focus on this slide.
Do you believe that slide and its title is in error?
If not, can you explain why if there is a non linear relationship between dose and concentration, such that that 3 dosed patients (even if they might have been on 10mg A2-73) achieved very close to 0 (zero) A2-73 contraction AND yet achieved improvement or reduced decline?
Also can you explain in your own words why you believe KEM and subsequently a Linear Mixed Model was used to derive conclusions about the combine results?
Do you believe that slide and its title is in error?
If not, can you explain why if there is a non linear relationship between dose and concentration, such that that 3 dosed patients (even if they might have been on 10mg A2-73) achieved very close to 0 (zero) A2-73 contraction AND yet achieved improvement or reduced decline?
Also can you explain in your own words why you believe KEM and subsequently a Linear Mixed Model was used to derive conclusions about the combine results?
