NorthWest Biotherapeutics Inc (NWBO)

[jondoeuk]

Can the armor thinge get T-cell infiltrate into tumor tissue? The answer is no. If there are no t cells, how could checking point inhibitors work? Is it simple enough to understand?

Preclinical data have shown the device results in damage-associated molecular patterns, and calreticulin (a pro-phagocytic signal) is increased on the surface of cancer cells. In addition, promoted the engulfment of cancer cells by DCs and their maturation in vitro, as well as recruitment of immune cells in vivo https://link.springer.com/article/10.1007/s00262-020-02534-7

The first of a number of combo (at least three or four) trials is already recruiting https://clinicaltrials.gov/ct2/show/NCT05004025