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Re: HyGro post# 559270

Sunday, 01/15/2023 1:50:30 AM

Sunday, January 15, 2023 1:50:30 AM

Post# of 822667
Biased manuscript against DCVax-L has no weighting factor.
First and foremost, this article appears to be biased by two individuals who rebuke Dr. Linda Liau's efforts regarding DCVax-L, IMPO.

"This one of the primary bias between the NWBO trial and the external comparators that did not require complete or near complete resection. This has been verified by researchers who have criticized the NWBO trial for considerable bias that raises serious questions of the trials validity.

Per H-G
"Read the peer-review article: https://academic.oup.com/neuro-oncology/advance-article/doi/10.1093/neuonc/noac281/6958519?searchresult=1";
Per H-G comments
"This one of the primary bias between the NWBO trial and the external comparators that did not require complete or near complete resection. This has been verified by researchers who have criticized the NWBO trial for considerable bias that raises serious questions of the trials validity."

There is not one reference to NWBO in this article
https://academic.oup.com/neuro-oncology/advance-article/doi/10.1093/neuonc/noac281/6958519?searchresult=1

There appears to be some biased overtones in this article, for example,

"Recently, Liau et al. reported data on autologous tumor lysateloaded dendritic cell vaccination (DCVax-L) in JAMA Oncology on November 17th 2022 and at the
27th Society of Neuro-Oncology (SNO) Annual meeting on November 20th 2022.2 While the efforts of
all contributors to the study need to be acknowledged, there are significant concerns about the
study report and conclusions."

These individuals fail to even address Dr. Linda Liau with any respect whatsoever.
They do address Dr. Linda Liau in their references.

Source
(1) Division of Oncology, Department of Medicine 1, Medical University, Vienna, Austria
(2) The Brain Tumour Center at the Erasmus MC Cancer Institute, Rotterdam

The above facilities hold zero weight in comparison to Dr. Linda Liau and her team at UCLA including NWBO and that is a fact, IMPO. In assents anyone can submit a rebuke article " Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination (DCVax-L) in glioblastoma:
breakthrough or fata morgana?"

Again, the research at UCLA and NWBO is far more credible than any research by "Martin J. van den Bent Brain Tumor Center at Erasmus MC Cancer Institute Dr Molenwaterplein 40
3015GD Rotterdam The Netherlands", IMPO. Anyone who knows anything with respect to the latest research for both nGBM and rGBM brain cancer. They know who Dr. Linda Liau and her team at UCLA are doing and they are considered one of the most advanced leading experts in the world in their field, and that is also a fact, IMPO. People need to do their own DD to understand the facts, and the fact that DCVax-L works, and many doctors, scientists and professionals are both impressed and agree with Dr. Linda Liau and NWBO, IMPO.
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