Peer-reviewed means the review panel of the journal review the manuscript prior to publication. It does not mean its a trial It does a comprehensive review of the trial and it's deficiencies.
Every well-qualified neuro-oncologist has participated in a trial with drug producers - All of the NWBO authors were directly or indirectly (through their medical facility) paid by NWBO . In fact much of the trial data processing and analysis was operated by a NWBO EMPLOYEE - Dr. Bosch -- that a violation of proper trial protocol - read the Neuro-Oncology Journal criticism. Read the JAMA Oncology article:
"Corresponding Author: Marnix L. Bosch, PhD, Northwest Biotherapeutics, Inc, 4800 Montgomery Ln, Bethesda, MD 20814 (marnix@nwbio.com).
Author Contributions: Dr Bosch had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis."
None of the "low preselects for long survival, old patients, patients with partial resection, recurred patients" would not have passed the NWBO trial screener. They had to be NAIVE GBM patients, had to be fully or close to fully resected -- read the screener. The recurrent patients were those that failed on comparator treatment (the control) and were dosed with DCVax-L
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