NorthWest Biotherapeutics Inc (NWBO)

[flipper44]

“So what changed?” — Hyperopia

This seems like a question DI could get to the bottom of for you, because it’s not material, imho, for the reason they already shared they can now transport across the pond. DI should run it past LP and Dr. Bosch and then answer your question.

This reminds me . . I’ve been a little skeptical of Linda Powers’ recent claim that patients in the US will have their treatments manufactured in the UK and vice versa. Northwest Bio has previously said in their SEC filings that regional manufacturing is necessary for that very reason; DCVax is manufactured using fresh monocytes that need to arrive to the manufacturing facility within 20 hours. So what changed?

Maybe the shipping couriers have improved their ability to deliver across the Atlantic within 24 hours, and Linda Powers was stretching a bit on their ability to distribute globally for the benefit of the regulators in Project Orbis.

Or maybe they don’t plan to use fresh monocytes. I wonder if one of the “bottle necks” that Advent is attempting to overcome for commercialization, involves comparability studies to show the equivalence of cryopreserved monocytes to fresh monocytes. I’ve discussed this previously a while back

. . .