Thursday, January 05, 2023 9:55:21 AM
It's mostly about safety. You may recall a few years ago, all of the media attention on Cox-2 inhibitors being implicated in significant cardiac events. Vioxx from Merck was the main one in the news. In the end, only one, Celebrex, survived.
https://www.npr.org/series/5033105/vioxx-the-downfall-of-a-drug#:~:text=June%208%2C%202006%20%E2%80%A2%20Merck,study%20and%20tell%20the%20public.
And besides, how does using a comparator that is not even available in the USA help us?
"Great minds discuss ideas
average minds discuss events
small minds discuss people"
- E. Roosevelt
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