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Re: Sparks68 post# 546088

Thursday, 12/08/2022 7:01:34 PM

Thursday, December 08, 2022 7:01:34 PM

Post# of 824194
You are not alone, per your comments,
"I still don’t really get the pseudo-progression argument. Why did they not see that in phase 1/2 trials? It should have been well known by phase 3, no? Liau herself said they saw it, but danced around it in her presentation Monday."
The original PFS, statistical objectives are just that, but the real results are the "OS data" , and they have proved to be more effective, and the main point is that the OS data supports the golden standard results. In other words, people are surviving longer. So, focusing on the OS date results is key factor, not the PFS, statistical objectives, IMPO.
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