NorthWest Biotherapeutics Inc (NWBO)

[CherryTree1]

This is interesting and seems challenging:

Merck & Co Inc (MRK.N) opted to jointly develop and potentially sell a personalized mRNA vaccine with Moderna Inc

If I understand how the mRNA covid vaccines work the target a small number of specific proteins (e.g. covid spike protein) that don't tend to change or mutate as frequently.. With what we have learned with DCVAX is that there could be 100's of target proteins and the cancer does tend to mutate at a fairly rapid pace . . . so this seems like they would need to expand the mRNA target proteins considerably or be left with a vaccine that appears to work initially but the the cancer reemerges from the mutations that are not covered by the vaccine. That is the beauty of leveraging the dendritic cells. They cover pretty much all the cancer unique proteins enabling our immune systems to target all of them.
Thanks my 2 cents.