Anavex Life Sciences Corp (AVXL)

[Steady_T]

I'm missing why you think the odds of an AA and P4 became lower.

We know that the FDA likes biochemical data. This seems to provide a lot of that. The activation of so many genes after dosing with 2-73 seems to provide MAJOR support for the MOA of 2-73. To me one of the weaknesses of the 2-73 story is what is the basis of the MOA. This data provides a solid basis for how 2-73 generates the results it seems to do.

I think the odds of an AA are not high in part because of the fiasco with Aduhelm. Even so I think the odds have improved rather than decreased.

I look forward to your thinking on this.