Sunday, July 31, 2022 1:46:45 PM
The poster shows increasing correlation between ALz and Pd, in particular between patients treated with A2-73. That is good for Anavex as the good PD/PDD data points to good results for the ALz trial.
In terms of the 'another trial needed', that keeps coming up here, but I thought I read an article saying that is not true. Also, it does not make sense to design a trial, with FDA input and acceptance, then with positive results, the FDA says OK very good but we dont believe it, do it again, then maybe we will believe it...or maybe you will have to run it again and again... !!?? Does not make sense.
I dont share your pessimism. All trials have had good outcomes. Some, rightly say, there were only 2 super responders in the original ALz trial, but one must understand the 'binning' or subgrouping of the data there, to understand what percentage of the general population of Alz patients that represents. There are probably 100s of people that have now been through the Alz OLE trial, so Dr.M probably has all kinds of data refining the original Alz data. Time will tell.
In terms of the 'another trial needed', that keeps coming up here, but I thought I read an article saying that is not true. Also, it does not make sense to design a trial, with FDA input and acceptance, then with positive results, the FDA says OK very good but we dont believe it, do it again, then maybe we will believe it...or maybe you will have to run it again and again... !!?? Does not make sense.
I dont share your pessimism. All trials have had good outcomes. Some, rightly say, there were only 2 super responders in the original ALz trial, but one must understand the 'binning' or subgrouping of the data there, to understand what percentage of the general population of Alz patients that represents. There are probably 100s of people that have now been through the Alz OLE trial, so Dr.M probably has all kinds of data refining the original Alz data. Time will tell.
Recent AVXL News
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- Anavex Life Sciences Submitted Request for EMA to Re-Examine Its Opinion • GlobeNewswire Inc. • 12/18/2025 12:30:00 PM
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