Friday, May 13, 2022 7:00:43 AM
So let me make sure I understand H2R.
Are you saying that for the external control group that any patient lost-to-follow-up is assumed to still be alive and that some of these trials didn't even track patients to 5 years or more whereas DCVAX had very few lost-to-follow-up?
That is ultraconservative and would clearly make DCVAX not look as good. It seems like the should have plotted the min and max line showing it assuming the lost-to-follow-up's are all alive and then assuming none are still alive. They could then show both graphs. Perhaps this will be discussed in detail in the journal article. I hope so. Even with the ultraconservative approach DCVAX is still clearly much than the historical SOC.
Thanks for posting this - GLTU.
Are you saying that for the external control group that any patient lost-to-follow-up is assumed to still be alive and that some of these trials didn't even track patients to 5 years or more whereas DCVAX had very few lost-to-follow-up?
That is ultraconservative and would clearly make DCVAX not look as good. It seems like the should have plotted the min and max line showing it assuming the lost-to-follow-up's are all alive and then assuming none are still alive. They could then show both graphs. Perhaps this will be discussed in detail in the journal article. I hope so. Even with the ultraconservative approach DCVAX is still clearly much than the historical SOC.
Thanks for posting this - GLTU.
Men who are occupied in the restoration of health to other men, by the joint exertion of skill and humanity, are above all the great of the earth. They even partake of divinity, since to preserve and renew is almost as noble as to create.
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