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Re: jimmy_mcyoloswag post# 351429

Wednesday, 02/16/2022 3:52:22 PM

Wednesday, February 16, 2022 3:52:22 PM

Post# of 518959
Yes. Very good presentation. Made everything crystal clear as to when things happened. Obviously this dumb rumor has been spread to the highest investor levels and is causing concern. Good that he cleared that up again. He asked when the last time they spoke to the FDA was and it’s been a while, but there was not need to. Now they will present a very compelling package.

I’m glad that Missling basically took a shat on Trofinetide. (Pun intended) I was surprised to hear that Trofinetide Did Not show any response in adults and Only showed a response in children. That says a lot about our drug. And what parent likes to have diarrhea and vomiting. For parents and children with Rett that’s a terrible side affect. NO ONE wants to deal with that, especially if they are sitting all the time. Quality of life for the caregiver and patient drops tremendously.

Also great that the moderator asked about the other biomarkers because they want to know how far reaching our drug will be. Those things make our cross CNS platform that much stronger. Missling laid that out nicely.

Also great that he emphasized the correlation between our PDD and Alz. “And those are our exact endpoints” mic drop moment. Although much of this we’ve heard so many times, it never gets old for me. And every time I hear it, I’m reassured that we will be winning. Winning so much, we may even get sick of winning.
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