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Post# of 828659
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flipper44

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Re: exwannabe post# 444466

Wednesday, 02/16/2022 3:10:21 PM

Wednesday, February 16, 2022 3:10:21 PM

Post# of 828659
The lymph system extends to the brain. This was discovered in 2015.

Further, DCs can exit the brain.

Mohammad MG, Tsai VWW, Ruitenberg MJ, et al. J Clin Invest 2014;124:1228–41http://dx.doi.org/10.1172/JCI71544 [PMC free article] [PubMed] [Google Scholar]


Evaluation of fluorescently labeled leukocyte migration in mice revealed that DCs travel via the RMS from the CNS to the cervical LNs (CxLNs), where they present antigen to T cells.

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