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Re: meirluc post# 439806

Sunday, 01/30/2022 9:59:53 PM

Sunday, January 30, 2022 9:59:53 PM

Post# of 822672

Data summarized from many studies show that only approximately 5.6% of primary glioblastoma are IDH1 mutant, while more than 76% of secondary glioblastomas carry the IDH1 mutation. https://www.frontiersin.org/articles/10.3389/fonc.2016.00016/full#h5



….mutations in one of the IDH genes are tightly linked with the Proneural phenotype and secondary glioblastomas. Virtually all tumors with IDH mutation are of the Proneural gene expression subtype. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109985/

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