Anavex Life Sciences Corp (AVXL)

[Investor2014]

From the paper abstract referenced on slide 4.

Glial cells, including microglia and astrocytes, play an increasingly recognized role in both the promotion and prevention of neurodegeneration. Sigma receptors, particularly the sigma-1 receptor subtype, which are expressed in both neurons and glia of multiple regions within the central nervous system, are a unique class of intracellular proteins that can modulate many biological mechanisms associated with neurodegeneration.

Role of sigma-1 receptors in neurodegenerative diseases