It is NWBO’s factory. Not Advent’s factory. Advent is a CDMO, is the operations manager, and is doing all of the work on the client’s (NWBO’s) site. Because the volume for compassionate use is going to be low, and because to get certified they need to have a certain level of resources online always, regardless of volume, and because this certification will also cover commercial use of the facilities, the cost is very high to get to this stage and maintain it the factory in pristine condition until it is turned on for fully approved DCVax commercial production. It can either all sit not being used but ready, or NWBO can allow their contracted CDMO, with inducements, to bear some of that cost in exchange for use of parts of the factory that are not in use and will not be during the period that production might be facilitated for other companies. The companies have a contractual arrangement in place, and they have future intent to find ways to keep the factory ready. The arrangement has been described but likely is not fully fleshed out because the factory has not yet been certified and has only been built out this year in anticipation of certification. Compensation can come in many forms. Not having to maintain the cost of all employees hired to maintain the site ir to do production could be a form of compensation. Once the factory is completed, depending on many other factors, Advent would still need customers who might use the excess space and they’d need to win those production contracts. Companies contracting with them might only be project by project and that might be a disadvantage for them. They will have to see.
So it’s basically hypothetical until it becomes a reality, and at such time, they need to get the permission of NWBO, via their contract and sub-contract arrangement and no doubt those arrangements will each be negotiated at the time they are relevant, on terms that are commercially realistic at that time.
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