My arguments have been that: 1) Anavex understands how well everyone is doing as over 95% signed up for the OLE, probably similar to PDD trial which showed significant numbers in a short period of time (12 weeks); 2) for an international study of 450 participants, it is strange that the first 225 were selected from only one country; this was obviously intentional with a specific, well-guarded reason for such action; 3) we don't know if Anavex is peeking or not as Dr. M does not give any hints of what Anavex is doing, other than offering a tidbit that it might peek; and 4) many people will go beyond a point in which blarcamesine might help them to recover/improve by waiting an additional 18 months for those final numbers. The numbers are the numbers whether a peek occurs or not.
Also, has anyone provided the name of a trial and sponsor that took a peek early, which caused its number to be non-significant at the end? If so, please re-state. TIA
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