NorthWest Biotherapeutics Inc (NWBO)

[anders2211]

No one is arguing that in due time DCVAX therapies will be overtaken and outdated by the next big cancer breakthrough. Heck, the human race would be lagging if it were not, in the future. As it was with Immu for Chemo so will it be for the next big technical breakthrough for Immu. If not then all the hundreds of billions of dollars invested in cancer research over the past 50 years have been in vain.

You are however oversimplifying a complex problem here, in your assumption that message RNA will be the next silver bullet for cancer and thus NWBO is short-lived. Why do we bother with medical trials? Not ONLY to prove if and how a certain therapy works but also how long and well it works for patients, In the case of GBM its extra years, OS for patients.

So how many phase 3 cancer mRNA therapies for GBM or any other cancer for that matter are out there? I have not found one. Heck, they haven't even started testing mRNA vaccines for cancer treatment on humans yet. You know why because they are still in early-stage where they have encountered many difficulties when it comes to mRNA

early mRNA oncology vaccine trials proved to be unsuccessful, with a significant proportion of studies (55.5%) being withdrawn or terminated from 2009 to 2016.

https://www.clinicaltrialsarena.com/comment/evolution-mrna-vaccine-trials-oncology/

So you asserting with great certainty that mRNA will overtake DCVAX soon is not based on any evidential study.

So when can we expect mRNA studies to be approved for GBM with the same OS or even better OS results as DCVAX-L if it would work? In 2040? 2045?
Hold my hat I will sell my NWBO shares coming Monday at any price lol...

BP will be happy to pay top dollar for DCVAX-L. Its better to have one working DCVAX bird for the next 20 years in the hand than perhaps in 20- 30 years produce the same result with a maybe working mRNA vaccine for cancer let alone GBM...