Anavex Life Sciences Corp (AVXL)

[falconer66a]

More undisclosed Anavex info.

From the European Patent Office: ANAVEX2-73 FOR THE TREATMENT OF GENETIC NEURODEVELOPMENTAL DISORDERS

Stunning. Makes no sense. Those of us who know a bit of the molecular mechanics of the referenced aneuploid genetic diseases want to know how Anavex sigma-1 receptor activators could possibly resolve the profound problems caused by anomalous numbers of chromosomes. Fixing dysfunctional homeostatic processes in nerves, by way of sigma-1 receptor activation, is one thing. Makes sense. Fixing, treating the neurodevelopment problems caused by aneuploidy, anomalous numbers of chromosomes, raises a host of questions.

Down's syndrome is mentioned. The condition is Trisomy-21, with an extra 21st chromosome. Normally, there is but a pair, one from each parent. With three, also sorts of development anomalies occur, the typical Down's syndrome symptoms. I'd sure like to understand how the Anavex molecules might help treat this condition. Can't see how it could disable or remove the complicating superfluous chromosome.

A mystery, for me, altogether. But I'm not concerned. Anavex isn't arbitrarily making up these things. I've perceived from the start that Anavex has behind their closed lab doors a multitude of trade-secret data on what diseases and conditions their drugs can favorably impact. There will be far more to the Anavex story than just sigma-1 receptor activation in neurons. Revelations of such in coming months and years are going to be astounding.